healtheo360 Wellness Blog

HER 2 + Breast Cancer: Quick Facts

Posted on Jan 4, 2016 12:25:56 AM by healtheo360

Did you know that about 20 percent of Breast Cancers are HER2-positive? Breast cancer does not only affect older women but also younger women as well. There are more HER2 cases in younger women than older women. The healtheo360 team has provided you with a few quick facts about the HER2-positive gene.

What is HER 2 + Breast Cancer?

HER 2 + is when you are tested positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer cells. The HER2 gene makes HER2 proteins, which are receptors on breasts cells. Normally, the HER2 receptors help to control how healthy a breast cell grows. But the overexpression of the HER2 protein will result in the pathology report as HER2 positive.

Is HER2 + hereditary?

HER2+ is not hereditary, but it’s a genetic mutation that occurs after conception. Having a close relative does not increase your chances of diagnosed.


There are a few examinations that you can take in order to find your diagnosis for HER2+, here are some of those examinations:

IHC TEST (Immuno Histo Chemistry) is able to find out if there is too many HER2 proteins in the cancer cells. The results of this exam can be negative, borderline, or positive.
FISH Test (Fluorescence In Situ Hybridization) can also find out if there is too many HER2 copies but the results are either negative or positive no borderline.
SPoT-Light HER2 CISH Test (Subtraction Probe Technology Chromogenic In Situ Hybridization)
Inform HER2 Dual ISH test (Inform Dual In Situ Hybridization)


Treatments that are specifically targeted to control the growth of HER2 genes are:

• Trastuzumab
• Lapatinib
• Pertuzumab
• Ado-trastuzmab emtansine


Here are a few preventative ways to help you avoid the diagnosis of Breast Cancer:


• Maintaining a healthy weight
• Eating well
• Exercising regularly
• Stop smoking if you are a smoker
• Reduce your alcohol consumption

Related Article:
Genetic Testing for Breast Cancer (Infographic)

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